Recombinant Human MITD1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MITD1-1265H
• Product Overview: MITD1 MS Standard C13 and N15-labeled recombinant protein (NP_620153) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.3 kDa
• AA Sequence: MAKSGLRQDPQSTAAATVLKRAVEL DSESRYPQALVCYQEGIDLLLQVLK GTKDNTKRCNLREKISKYMDRAENI KKYLDQEKEDGKYHKQIKIEENATG FSYESLFREYLNETVTEVWIEDPYI RHTHQLYNFLRFCEMLIKRPCKVKT IHLLTSLDEGIEQVQQSRGLQEIEE SLRSHGVLLEVQYSSSIHDREIRFN NGWMIKIGRGLDYFKKPQSRFSLGY CDFDLRPCHETTVDIFHKKHTKNIT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MITD1 microtubule interacting and trafficking domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: MITD1
• Synonyms: MITD1; MIT, microtubule interacting and transport, domain containing 1; MIT domain-containing protein 1; LOC129531
• Gene ID: 129531
• mRNA Refseq: NM_138798
• Protein Refseq: NP_620153
• UniProt ID: Q8WV92