Recombinant Human MITF Protein (Met1-Cys520), N-His tagged, Biotinylated

• Cat.No.: MITF-2446HB
• Product Overview: Biotinylated recombinant Human MITF Protein (Met1-Cys520) with N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Solution
• Molecular Mass: Predicted Molecular Mass: 61.9 kDa
  Accurate Molecular Mass: 62 kDa
• Protein Length: Met1-Cys520
• Endotoxin: < 1.0 EU/μg of the protein by the LAL method.
• Purity: > 95%
• Applications: Positive Control, Immunogen, SDS-PAGE, WB
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Aliquot andstore below -20 centigrade for 12 months.
• Concentration: 0.99 mg/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: MITF microphthalmia-associated transcription factor [ Homo sapiens (human) ]
• Official Symbol: MITF
• Synonyms: MITF; microphthalmia-associated transcription factor; Waardenburg syndrome, type 2A, WS2, WS2A; bHLHe32; homolog of mouse microphthalmia; MI; class E basic helix-loop-helix protein 32; WS2; WS2A
• Gene ID: 4286
• mRNA Refseq: NM_000248
• Protein Refseq: NP_000239
• MIM: 156845
• UniProt ID: O75030