Recombinant Human MKK6, Gly & Pro tagged
Cat.No. : | MAP2K6-525H |
Product Overview : | Recombinant Human MKK6 (NP_002749.2) (Met1-Asp334), fused with two additional amino acids (Gly & Pro) at the N-terminus, was produced in Baculovirus-Insect cells. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect cells |
Species : | Human |
Tag : | Gly & Pro |
Predicted N Terminal : | Gly |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. |
Molecular Mass : | The secreted recombinant human MKK6 consists of 336 amino acids and predicts a molecular mass of 37.6 KDa. The apparent molecular mass of the protein is approximately 37 KDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | MAP2K6 mitogen-activated protein kinase kinase 6 [ Homo sapiens(human) ] |
Official Symbol : | MKK6 |
Gene ID : | 5608 |
mRNA Refseq : | NM_002758 |
Protein Refseq : | NP_002749 |
MIM : | 601254 |
UniProt ID : | P52564 |
Chromosome Location : | 17q24.3 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIts expression levels in certain cancers are being explored as predictive biomarkers to anticipate response to specific therapies.
Studies also suggest its involvement in cardiovascular diseases and neurological disorders.
MAP2K6 signaling pathways might play a role in drug resistance mechanisms, making it a focus for overcoming therapeutic challenges.
Yes, mutations in MAP2K6 have been linked to certain cancers, including colorectal cancer and lung adenocarcinoma.
As with any targeted therapy, MAP2K6 inhibitors might have side effects, which are under investigation in preclinical and clinical studies.
Customer Reviews (3)
Write a reviewI am certain that the MAP2K6 protein will play a pivotal role in facilitating robust and insightful research, providing the assurance of reliable and consistent results.
The excellent technical support provided by the manufacturer can solve my problem.
Whether I am studying protein-protein interactions, investigating cellular pathways, or examining protein folding dynamics, the MAP2K6 protein consistently delivers exceptional performance and precise outcomes.
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