Recombinant Human MLANA Protein, His (Fc)-Avi-tagged

• Cat.No.: MLANA-1417H
• Product Overview: Recombinant Human MLANA with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: MLANA melan-A [ Homo sapiens (human) ]
• Official Symbol: MLANA
• Synonyms: MART1; MART-1
• Gene ID: 2315
• mRNA Refseq: NM_005511.2
• Protein Refseq: NP_005502.1
• MIM: 605513
• UniProt ID: Q16655

Reviews

01/13/2022

The labeling effect is excellent in Western blot, and fluorescent labeling can be performed.

01/03/2022

The stability of MLANA is excellent and adaptable under a variety of conditions.

04/07/2021

Good expression level and stability in clonal expression.

Q&As

How does MLANA interact with other proteins?

MLANA can interact with a variety of other proteins, including proteins on mitochondrial membranes, members of the Bcl-2 family, and caspases. These interactions allow it to regulate processes such as mitochondrial dynamics and apoptosis.

What role does MLANA play in cancer?

Studies have shown that the expression level of MLANA is upregulated in some cancers, which may be related to the occurrence and development of tumors. It could be a potential target for cancer treatment.

What's the treatment strategy for MLANA?

Therapeutic strategies for MLANA include inhibiting its expression, inhibiting its interaction with specific proteins, and targeting degradation. These approaches may have potential applications for certain cancer treatments.

Is there a relationship between the structure and function of MLANA?

The structure of MLANA determines its ability to interact with other proteins on the mitochondrial membrane and its function. The study of its structure can help us understand its function and mechanism of action.

How is the expression level of MLANA regulated?

The expression level of MLANA can be regulated in a variety of ways, including transcription, post-transcriptional modification, and degradation. These processes may involve various molecules such as transcription factors, regulatory Rnas, and signal transduction pathways.

How does MLANA participate in mitochondrial homeostasis?

MLANA can interact with a variety of proteins on the mitochondrial membrane to regulate the fusion and division of mitochondria, thus maintaining the homeostasia of mitochondria.