Recombinant Human MMP15 Protein, His/GST-tagged

• Cat.No.: MMP15-459H
• Product Overview: Recombinant Human MMP15(Phe280~Asp497) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.
• Source: E. coli
• Species: Human
• Tag: His/GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 58.0kDa
• Identity: Reconstitute in PBS or others
• Protein length: Phe280~Asp497
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: MMP15 matrix metallopeptidase 15 (membrane-inserted) [ Homo sapiens ]
• Official Symbol: MMP15
• Synonyms: MMP15; matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15 (membrane inserted); matrix metalloproteinase-15; MT2 MMP; MTMMP2; SMCP 2; MMP-15; MT2MMP; MT-MMP 2; membrane-type matrix metalloproteinase 2; membrane-type-2 matrix metalloproteinase; matrix metalloproteinase 15 (membrane-inserted); SMCP-2; MT2-MMP
• Gene ID: 4324
• mRNA Refseq: NM_002428
• Protein Refseq: NP_002419
• MIM: 602261
• UniProt ID: P51511