Active Recombinant Human MMP17 protein, His-tagged

• Cat.No.: MMP17-26H
• Product Overview: Recombinant Human MMP17 (Ala39-Ser531 (Arg125Pro) & (Ala182Thr)) fused with His tag at C-terminal was expressed in NS0.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ala39
• Form: Supplied as a 0.2 μm filtered solution in MES, NaCl, CaCl2 and Glycerol.
• Bio-activity: Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is >150 pmol/min/μg.
• Molecular Mass: Predicted Molecular Mass: 47 kDa;SDS-PAGE: 56-65 kDa, reducing conditions.
• Purity: >80%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane.
• Stability: Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 centigrade as supplied.3 months, -20 to -70 centigrade under sterile conditions after opening.

Gene Information

• Gene Name: MMP17 matrix metallopeptidase 17 (membrane-inserted) [ Homo sapiens ]
• Official Symbol: MMP17
• Synonyms: MMP17; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17 (membrane inserted); matrix metalloproteinase-17; MT4 MMP; MMP-17; MT4MMP; MTMMP4; MT-MMP 4; membrane-type matrix metalloproteinase 4; membrane-type-4 matrix metalloproteinase; matrix metalloproteinase 17 (membrane-inserted); MT4-MMP
• Gene ID: 4326
• mRNA Refseq: NM_016155
• Protein Refseq: NP_057239
• MIM: 602285
• UniProt ID: Q9ULZ9
• Chromosome Location: 12q24.3
• Pathway: Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem
• Function: calcium ion binding; enzyme activator activity; metalloendopeptidase activity; peptidase activity; zinc ion binding