Recombinant Human MMP3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | MMP3-780H |
Product Overview : | MMP3 MS Standard C13 and N15-labeled recombinant protein (NP_002413) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 54 kDa |
AA Sequence : | MKSLPILLLLCVAVCSAYPLDGAAR GEDTSMNLVQKYLENYYDLEKDVKQ FVRRKDSGPVVKKIREMQKFLGLEV TGKLDSDTLEVMRKPRCGVPDVGHF RTFPGIPKWRKTHLTYRIVNYTPDL PKDAVDSAVEKALKVWEEVTPLTFS RLYEGEADIMISFAVREHGDFYPFD GPGNVLAHAYAPGPGINGDAHFDDD EQWTKDTTGTNLFLVAAHEIGHSLG LFHSANTEALMYPLYHSLTDLTRFR LSQDDINGIQSLYGPPPDSPETPLV PTEPVPPEPGTPANCDPALSFDAVS TLRGEILIFKDRHFWRKSLRKLEPE LHLISSFWPSLPSGVDAAYEVTSKD LVFIFKGNQFWAIRGNEVRAGYPRG IHTLGFPPTVRKIDAAISDKEKNKT YFFVEDKYWRFDEKRNSMEPGFPKQ IAEDFPGIDSKIDAVFEEFGFFYFF TGSSQLEFDPNAKKVTHTLKSNSWL NCTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | MMP3 matrix metallopeptidase 3 [ Homo sapiens (human) ] |
Official Symbol : | MMP3 |
Synonyms : | MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 (stromelysin 1, progelatinase), STMY, STMY1; stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; MGC126102; MGC126103; MGC126104; |
Gene ID : | 4314 |
mRNA Refseq : | NM_002422 |
Protein Refseq : | NP_002413 |
MIM : | 185250 |
UniProt ID : | P08254 |
Products Types
◆ Recombinant Protein | ||
MMP3-5433H | Recombinant Human MMP3 Protein, GST-tagged | +Inquiry |
Mmp3-7422R | Recombinant Rat Mmp3 protein, His-tagged | +Inquiry |
MMP3-2449H | Recombinant Human MMP3 Protein, His-tagged | +Inquiry |
MMP3-1420H | Recombinant Human MMP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP3-555H | Recombinant Human MMP3 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
MMP3-26C | Native Clostridium histolyticum Collagenase Type 3 Protein | +Inquiry |
◆ Lysates | ||
MMP3-4273HCL | Recombinant Human MMP3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2213 | MMP-3 Activity Fluorometric Assay Kit | +Inquiry |
Kit-0589 | MMP-3 Activity Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMMP3 breaks down extracellular matrix components, aiding in tissue remodeling and repair.
MMP3 facilitates cancer metastasis by altering the tumor microenvironment and promoting invasion.
Changes in MMP3 activity can accelerate skin aging and contribute to dermatological conditions.
MMP3 influences cardiovascular health by affecting arterial wall remodeling and stability.
MMP3 contributes to arthritis progression by degrading joint cartilage and connective tissues.
MMP3 modulates inflammation, impacting tissue inflammation and repair processes.
MMP3 plays a role in wound healing by remodeling damaged tissues and aiding in repair.
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