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Recombinant Human MOCOS Protein, GST-tagged

Cat.No. : MOCOS-5462H
Product Overview : Human MOCOS full-length ORF ( AAH12079.1, 1 a.a. - 888 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine. [provided by RefSeq, Apr 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 124.6 kDa
AA Sequence : MAGAAAESGRELWTFAGSRDPSAPR LAYGYGPGSLRELRAREFSRLAGTV YLDHAGATLFSQSQLESFTSDLMEN TYGNPHSQNISSKLTHDTVEQVRYR ILAHFHTTAEDYTVIFTAGSTAALK LVAEAFPWVSQGPESSGSRFCYLTD SHTSVVGMRNVTMAINVISIPVRPE DLWSAEERGASASNPDCQLPHLFCY PAQSNFSGVRYPLSWIEEVKSGRLR PVSTPGKWFVLLDAASYVSTSPLDL SAHQADFVPISFYKIFGFPTGLGAL LVHNRAAPLLRKTYFGGGTASAYLA GEDFYIPRQSVAQRFEDGTISFLDV IALKHGFDTLERLTGGMENIKQHTF TLAQYTYMALSSLQYPNGAPVVRIY SDSEFSSPEVQGPIINFNVLDDKGN IIGYSQVDKMASLYNIHLRTGCFCN TGACQRHLGISNEMVRKHFQAGHVC GDNMDLIDGQPTGSVRISFGYMSTL DDVQAFLRFIIDTRLHSSGDWPVPQ AHADTGETGAPSADSQADVIPAVMG RRSLSPQEDALTGSRVWNNSSTVNA VPVAPPVCDVARTQPTPSEKAAGVL EGALGPHVVTNLYLYPIKSCAAFEV TRWPVGNQGLLYDRSWMVVNHNGVC LSQKQEPRLCLIQPFIDLRQRIMVI KAKGMEPIEVPLEENSERTQIRQSR VCADRVSTYDCGEKISSWLSTFFGR PCHLIKQSSNSQRNAKKKHGKDQLP GTMATLSLVNEAQYLLINTSSILEL HRQLNTSDENGKEELFSLKDLSLRF RANIIINGKRAFEEEKWDEISIGSL RFQVLGPCHRCQMICIDQQTGQRNQ HVFQKLSESRETKVNFGMYLMHASL DLSSPCFLSVGSQVLPVLKENVEGH DLPASEKHQDVTS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MOCOS molybdenum cofactor sulfurase [ Homo sapiens ]
Official Symbol : MOCOS
Synonyms : MOCOS; molybdenum cofactor sulfurase; MCS; MOS; HMCS; moCo sulfurase; EC 2.8.1.9; EC 3.4.25.1; hMCS; FLJ20733
Gene ID : 55034
mRNA Refseq : NM_017947
Protein Refseq : NP_060417
MIM : 613274
UniProt ID : Q96EN8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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