Recombinant Human MRPS22 Protein, GST-tagged

• Cat.No.: MRPS22-5610H
• Product Overview: Human MRPS22 full-length ORF ( AAH09296, 1 a.a. - 360 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.34 kDa
• AA Sequence: MAPLGTTVLLWSLLRSSPGVERVCF RARIQPWHGGLLQPLPCSFEMGLPR RRFSSEAAESGSPETKKPTFMDEEV QSILTKMTGLNLQKTFKPAIQELKP PTYKLMTQAQLEEATRQAVEAAKVR LKMPPVLEERVPINDVLAEDKILEG TETTKYVFTDISYSIPHRERFIVVR EPSGTLRKASWEERDRMIQVYFPKE GRKILTPIIFKEENLRTMYSQDRHV DVLNLCFAQFEPDSTEYIKVHHKTY EDIDKRGKYDLLRSTRYFGGMVWYF VNNKKIDGLLIDQIQRDLIDDATNL VQLYHVLHPDGQSAQGAKDQAAEGI NLIKVFAKTEAQKGAYIELTLQTYQ EALSRHSAAS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MRPS22 mitochondrial ribosomal protein S22 [ Homo sapiens ]
• Official Symbol: MRPS22
• Synonyms: MRPS22; mitochondrial ribosomal protein S22; 28S ribosomal protein S22, mitochondrial; C3orf5; GIBT; GK002; MRP S22; S22mt; COXPD5; RPMS22; MRP-S22
• Gene ID: 56945
• mRNA Refseq: NM_020191
• Protein Refseq: NP_064576
• MIM: 605810
• UniProt ID: P82650