Recombinant Human MS4A2 Protein, GST-tagged
Cat.No. : | MS4A2-5634H |
Product Overview : | Human MS4A2 full-length ORF ( NP_000130.1, 1 a.a. - 244 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 52.9 kDa |
AA Sequence : | MDTESNRRANLALPQEPSSVPAFEV LEISPQEVSSGRLLKSASSPPLHTW LTVLKKEQEFLGVTQILTAMICLCF GTVVCSVLDISHIEGDIFSSFKAGY PFWGAIFFSISGMLSIISERRNATY LVRGSLGANTASSIAGGTGITILII NLKKSLAYIHIHSCQKFFETKCFMA SFSTEIVVMMLFLTILGLGSAVSLT ICGAGEELKGNKVPEDRVYEELNIY SATYSELEDPGEMSPPIDL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MS4A2 membrane-spanning 4-domains, subfamily A, member 2 [ Homo sapiens ] |
Official Symbol : | MS4A2 |
Synonyms : | MS4A2; membrane-spanning 4-domains, subfamily A, member 2; APY, FCER1B, IgE responsiveness (atopic) , IGER, membrane spanning 4 domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide); high affinity immunoglobulin epsilon receptor subunit beta; Fc fragment of IgE; high affinity I; receptor for; beta polypeptide; MS4A1; igE Fc receptor subunit beta; high affinity IgE receptor beta subunit; immunoglobulin E receptor, high affinity, beta polypeptide; Fc fragment of IgE, high affinity I, receptor for; beta polypeptide; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain); APY; IGEL; IGER; ATOPY; FCERI; IGHER; FCER1B; |
Gene ID : | 2206 |
mRNA Refseq : | NM_000139 |
Protein Refseq : | NP_000130 |
MIM : | 147138 |
UniProt ID : | Q01362 |
Products Types
◆ Recombinant Protein | ||
MS4A2-3444R | Recombinant Rat MS4A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MS4A2-3785R | Recombinant Rat MS4A2 Protein | +Inquiry |
MS4A2-151H | Recombinant Human MS4A2 Protein, DYKDDDDK-tagged | +Inquiry |
◆ Lysates | ||
MS4A2-4126HCL | Recombinant Human MS4A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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