Description : |
This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
59.8 kDa |
AA Sequence : |
MSASEGMKFKFHSGEKVLCFEPDPT KARVLYDAKIVDVIVGKDEKGRKIP EYLIHFNGWNRSWDRWAAEDHVLRD TDENRRLQRKLARKAVARLRSTGRK KKRCRLPGVDSVLKGLPTEEKDEND ENSLSSSSDCSENKDEEISEESDIE EKTEVKEEPELQTRREMEERTITIE IPEVLKKQLEDDCYYINRRKRLVKL PCQTNIITILESYVKHFAINAAFSA NERPRHHHVMPHANMNVHYIPAEKN VDLCKEMVDGLRITFDYTLPLVLLY PYEQAQYKKVTSSKFFLPIKESATS TNRSQEELSPSPPLLNPSTPQSTES QPTTGEPATPKRRKAEPEALQSLRR STRHSANCDRLSESSASPQPKRRQQ DTSASMPKLFLHLEKKTPVHSRSSS PIPLTPSKEGSAVFAGFEGRRTNEI NEVLSWKLVPDNYPPGDQPPPPSYI YGAQHLLRLFVKLPEILGKMSFSEK NLKALLKHFDLFLRFLAEYHDDFFP ESAYVAACEAHYSTKNPRAIYTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |