Recombinant Human MSX2 cell lysate

• Cat.No.: MSX2-1141HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: MSX2 msh homeobox 2 [ Homo sapiens ]
• Official Symbol: MSX2
• Synonyms: MSX2; msh homeobox 2; msh (Drosophila) homeo box homolog 2 , msh homeobox homolog 2 (Drosophila) , parietal foramina 1 , PFM1; homeobox protein MSX-2; craniosynostosis; type 2; CRS2; FPP; HOX8; MSH; PFM; msh homeo box 2; homeobox protein Hox-8; msh homeobox homolog 2; PFM1
• Gene ID: 4488
• mRNA Refseq: NM_002449
• Protein Refseq: NP_002440
• MIM: 123101
• UniProt ID: P35548
• Chromosome Location: 5q35.2
• Pathway: HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding