Recombinant Mouse Msx2 Protein, Myc/DDK-tagged

• Cat.No.: Msx2-4200M
• Product Overview: Purified recombinant protein of mouse full-length msh homeobox 2 (Msx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 29.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Msx2 msh homeobox 2 [ Mus musculus (house mouse) ]
• Official Symbol: Msx2
• Synonyms: MSX2; homeobox, msh-like 2; homeobox protein MSX-2; homeo box, msh-like 2; homeobox protein Hox-8-1; Hox8; Hox-8; Hox8.1; BB122635
• Gene ID: 17702
• mRNA Refseq: NM_013601
• Protein Refseq: NP_038629
• UniProt ID: Q03358