"MTA1" Related Products


Recombinant Human MTA1 protein, MYC/DDK-tagged

Cat.No.: MTA1-2943H
Product Overview: Recombinant human full length (a.a.1-715) MAT1 was expressed in HEK293 cells with C-terminal MYC/DDK tag. This protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Description: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 80.6 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: MTA1 metastasis associated 1 [ Homo sapiens ]
Official Symbol: MTA1
Synonyms: MTA1; metastasis associated 1; metastasis-associated protein MTA1
Gene ID: 9112
mRNA Refseq: NM_001203258
Protein Refseq: NP_004680
MIM: 603526
UniProt ID: Q13330

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