Recombinant Human MTF1 Protein, GST-tagged

• Cat.No.: MTF1-5696H
• Product Overview: Human MTF1 full-length ORF (BAG36903.1, 1 a.a. - 753 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 109.23 kDa
• AA Sequence: MGEHSPDNNIIYFEAEEDELTPDDK MLRFVDKNGLVPSSSGTVYDRTTVL IEQDPGTLEDEDDDGQCGEHLPFLV GGEEGFHLIDHEAMSQGYVQHIISP DQIHLTINPGSTPMPRNIEGATLTL QSECPETKRKEVKRYQCTFEGCPRT YSTAGNLRTHQKTHRGEYTFVCNQE GCGKAFLTSYSLRIHVRVHTKEKPF ECDVQGCEKAFNTLYRLKAHQRLHT GKTFNCESEGCSKYFTTLSDLRKHI RTHTGEKPFRCDHDGCGKAFAASHH LKTHVRTHTGERPFFCPSNGCEKTF STQYSLKSHMKGHDNKGHSYNALPQ HNGSEDTNHSLCLSDLSLLSTDSEL RENSSTTQGQDLSTISPAIIFESMF QNSDDTAIQEDPQQTASLTESFNGD AESVSDVPPSTGNSASLSLPLVLQP GLSEPPQPLLPASAPSAPPPAPSLG PGSQQAAFGNPPALLQPPEVPVPHS TQFAANHQEFLPHPQAPQPIVPGLS VVAGASASAAAVASAVAAPAPPQST TEPLPAMVQTLPLGANSVLTNNPTI TITPTPNTAILQSSLVMGEQNLQWI LNGATSSPQNQEQIQQASKVEKVFF TTAVPVASSPGSSVQQIGLSVPVII IKQEEACQCQCACRDSAKERASSRR KGCSSPPPPEPSPQAPDGPSLQLPA QTFSSAPVPGSSSSTLPSSCEQSRQ AETPSDPQTETLSAMDVSEFLSLQS LDTPSNLIPIEALLQGEEEMGLTSS FSK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MTF1 metal-regulatory transcription factor 1 [ Homo sapiens ]
• Official Symbol: MTF1
• Synonyms: MTF1; metal-regulatory transcription factor 1; metal regulatory transcription factor 1; zinc regulatory factor; transcription factor MTF-1; MRE-binding transcription factor; MRE-binding transcription factor-1; metal-responsive transcription factor 1; ZRF; MTF-1; MGC23036
• Gene ID: 4520
• mRNA Refseq: NM_005955
• Protein Refseq: NP_005946
• MIM: 600172
• UniProt ID: Q14872