Recombinant Human MTMR3 cell lysate

• Cat.No.: MTMR3-1148HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: MTMR3 myotubularin related protein 3 [ Homo sapiens ]
• Official Symbol: MTMR3
• Synonyms: MTMR3; myotubularin related protein 3; myotubularin-related protein 3; FYVE DSP1; KIAA0371; ZFYVE10; zinc finger, FYVE domain containing 10; zinc finger FYVE domain-containing protein 10; FYVE domain-containing dual specificity protein phosphatase 1; FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase; FYVE-DSP1; FLJ32333
• Gene ID: 8897
• mRNA Refseq: NM_021090
• Protein Refseq: NP_066576
• MIM: 603558
• UniProt ID: Q13615
• Chromosome Location: 22q12.2
• Pathway: 3-phosphoinositide degradation, organism-specific biosystem; 3-phosphoinositide degradation, conserved biosystem; D-myo-inositol-5-phosphate metabolism, organism-specific biosystem; D-myo-inositol-5-phosphate metabolism, conserved biosystem; superpathway of inositol phosphate compounds, organism-specific biosystem
• Function: hydrolase activity; metal ion binding; phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity