Recombinant Human MTPN Protein, MYC/DDK-tagged

• Cat.No.: MTPN-2180H
• Product Overview: Recombinant human MTPN protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 12.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MTPN myotrophin [ Homo sapiens ]
• Official Symbol: MTPN
• Synonyms: GCDP; V-1
• Gene ID: 94351
• mRNA Refseq: NM_145808.3
• Protein Refseq: NP_665807
• MIM: 606484
• UniProt ID: P58546