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Recombinant Human MUC1 protein(Met 1-Gly 167)

Cat.No. : MUC1-448H
Product Overview : Recombinant Human MUC1 protein(NP_001018016.1)(Met 1-Gly 167) was expressed in HEK293.
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  • Gene Information
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similar : MUC1
Alias : MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC;
Source : HEK293
Species : Human
Conjugate : N/A
Tag : N/A
Protein length : Met 1-Gly 167
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
MolecularMass : The recombinant human MUC1 consists of 142 amino and has a predicted molecular mass of 15.4 kDa.
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
GeneName : MUC1 mucin 1, cell surface associated [ Homo sapiens ]
GeneNameWeblink : 4582
OfficialSymbol : MUC1
OfficialSymbolWeblink : 4582
GeneID : 4582
GeneIDWeblink : 4582
mRNARefseq : NM_001018016
mRNARefseqWeblink : NM_001018016.2
ProteinRefseqWeblink : NP_001018016.1
MIMWeblink : 158340
UniProtID : P15941
UniProtIDWeblink : P15941
Synonyms : MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC;
MIM : 158340
Synonyms : MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC;
MIM : 158340

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the structural characteristics of the MUC1 protein? 11/12/2019

The MUC1 protein consists of a short extracellular region, a transmembrane region, and a long intracellular region. The extracellular region is rich in sugar chains, which make the MUC1 protein adherent.

What is the role of the MUC1 protein in cancer? 10/16/2019

In cancer, the expression of the MUC1 protein usually increases abnormally and changes in glycosylation occur. This can affect cell adhesion, proliferation, and invasion, promoting the spread and metastasis of cancer cells.

Is the MUC1 protein involved in the immune system? 09/02/2019

Yes, the MUC1 protein is closely related to the immune system. In some cases, abnormal expression of the MUC1 protein may interfere with the function of immune cells, thereby reducing the immune response.

In which diseases is MUC1 involved in the diagnosis and treatment? 08/17/2019

MUC1 protein is overexpressed in many types of cancer, including breast, stomach, ovarian, and others. Therefore, the MUC1 protein can be a potential target for cancer diagnosis and treatment.

What are the main physiological functions of MUC1 protein? 06/22/2019

The MUC1 protein mainly plays the role of protecting and lubricating the mucosal surface. It prevents bacteria and other pathogens from entering our body, while also helping to maintain cell-to-cell adhesion.

Is the MUC1 protein associated with other diseases? 06/01/2019

MUC1 protein may be associated with a number of other diseases, such as lung infections and inflammatory bowel disease. However, the research related to cancer is more extensive and in-depth.

Customer Reviews (3)

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Reviews
03/11/2022

    It is suitable for crystallography research and has good crystallinity.

    02/04/2022

      Target immune responses can be successfully induced.

      06/04/2019

        Enzymatic experiments showed that the catalytic efficiency was high

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