Recombinant Human MUC12 Protein, His-tagged

• Cat.No.: MUC12-2461H
• Product Overview: Recombinant Human MUC12 Protein (Ser5261-Val5335) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ser5261-Val5335
• Description: This gene encodes an integral membrane glycoprotein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces and have been implicated in epithelial renewal and differentiation. These glycoproteins also play a role in intracellular signaling. This protein is expressed on the apical membrane surface of epithelial cells that line the mucosal surfaces of many different tissues including the colon, pancreas, prostate, and uterus. The expression of this gene is downregulated in colorectal cancer tissue.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.4 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: MUC12 mucin 12, cell surface associated [ Homo sapiens (human) ]
• Official Symbol: MUC12
• Synonyms: MUC12; mucin 12, cell surface associated; MUC11; MUC-11; MUC-12; mucin-12
  mucin-11
• Gene ID: 10071
• mRNA Refseq: NM_001164462
• Protein Refseq: NP_001157934
• MIM: 604609
• UniProt ID: Q9UKN1