Recombinant Human MUC12 Protein, GST-tagged

• Cat.No.: MUC12-5746H
• Product Overview: Human MUC12 partial ORF ( XP_379904.2, 391 a.a. - 465 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an integral membrane glycoprotein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces and have been implicated in epithelial renewal and differentiation. These glycoproteins also play a role in intracellular signaling. This protein is expressed on the apical membrane surface of epithelial cells that line the mucosal surfaces of many different tissues including the colon, pancreas, prostate, and uterus. The expression of this gene is downregulated in colorectal cancer tissue. [provided by RefSeq, Apr 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 33.99 kDa
• AA Sequence: SQRKRHREQYDVPQEWRKEGTPGIF QKTAIWEDQNLRESRFGLENAYNNF RPTLETVDSGTELHIQRPEMVASTV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MUC12 mucin 12, cell surface associated [ Homo sapiens (human) ]
• Official Symbol: MUC12
• Synonyms: MUC12; mucin 12, cell surface associated; MUC11; MUC-11; MUC-12; mucin-12; mucin-11
• Gene ID: 10071
• mRNA Refseq: NM_001164462
• Protein Refseq: NP_001157934
• MIM: 604609
• UniProt ID: Q9UKN1