| Description : |
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
82.1 kDa |
| AA Sequence : |
MSKAHKPWPYRRRSQFSSRKYLKKE MNSFQQQPPPFGTVPPQMMFPPNWQ GAEKDAAFLAKDFNFLTLNNQPPPG NRSQPRAMGPENNLYSQYEQKVRPC IDLIDSLRALGVEQDLALPAIAVIG DQSSGKSSVLEALSGVALPRGSGIV TRCPLVLKLKKQPCEAWAGRISYRN TELELQDPGQVEKEIHKAQNVMAGN GRGISHELISLEITSPEVPDLTIID LPGITRVAVDNQPRDIGLQIKALIK KYIQRQQTINLVVVPCNVDIATTEA LSMAHEVDPEGDRTIGILTKPDLMD RGTEKSVMNVVRNLTYPLKKGYMIV KCRGQQEITNRLSLAEATKKEITFF QTHPYFRVLLEEGSATVPRLAERLT TELIMHIQKSLPLLEGQIRESHQKA TEELRRCGADIPSQEADKMFFLIEK IKMFNQDIEKLVEGEEVVRENETRL YNKIREDFKNWVGILATNTQKVKNI IHEEVEKYEKQYRGKELLGFVNYKT FEIIVHQYIQQLVEPALSMLQKAME IIQQAFINVAKKHFGEFFNLNQTVQ STIEDIKVKHTAKAENMIQLQFRME QMVFCQDQIYSVVLKKVREEIFNPL GTPSQNMKLNSHFPSNESSVSSFTE IGIHLNAYFLETSKRLANQIPFIIQ YFMLRENGDSLQKAMMQILQEKNRY SWLLQEQSETATKRRILKERIYRLT QARHALCQFSSKEIHTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
