| Description : |
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
78.8 kDa |
| AA Sequence : |
MSRRTRCEDLDELHYQDTDSDVPEQ RDSKCKVKWTHEEDEQLRALVRQFG QQDWKFLASHFPNRTDQQCQYRWLR VLNPDLVKGPWTKEEDQKVIELVKK YGTKQWTLIAKHLKGRLGKQCRERW HNHLNPEVKKSCWTEEEDRIICEAH KVLGNRWAEIAKMLPGRTDNAVKNH WNSTIKRKVDTGGFLSESKDCKPPV YLLLELEDKDGLQSAQPTEGQGSLL TNWPSVPPTIKEEENSEEELAAATT SKEQEPIGTDLDAVRTPEPLEEFPK REDQEGSPPETSLPYKWVVEAANLL IPAVGSSLSEALDLIESDPDAWCDL SKFDLPEEPSAEDSINNSLVQLQAS HQQQVLPPRQPSALVPSVTEYRLDG HTISDLSRSSRGELIPISPSTEVGG SGIGTPPSVLKRQRKRRVALSPVTE NSTSLSFLDSCNSLTPKSTPVKTLP FSPSQFLNFWNKQDTLELESPSLTS TPVCSQKVVVTTPLHRDKTPLHQKH AAFVTPDQKYSMDNTPHTPTPFKNA LEKYGPLKPLPQTPHLEEDLKEVLR SEAGIELIIEDDIRPEKQKRKPGLR RSPIKKVRKSLALDIVDEDVKLMMS TLPKSLSLPTTAPSNSSSLTLSGIK EDNSLLNQGFLQAKPEKAAVAQKPR SHFTTPAPMSSAWKTVACGGTRDQL FMQEKARQLLGRLKPSHTSRTLILS TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
