| Description : |
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
126.5 kDa |
| AA Sequence : |
MPEPTKKEENEVPAPAPPPEEPSKE KEAGTTPAKDWTLVETPPGEEQAKQ NANSQLSILFIEKPQGGTVKVGEDI TFIAKVKAEDLLRKPTIKWFKGKWM DLASKAGKHLQLKETFERHSRVYTF EMQIIKAKDNFAGNYRCEVTYKDKF DSCSFDLEVHESTGTTPNIDIRSAF KRSGEGQEDAGELDFSGLLKRREVK QQEEEPQVDVWELLKNAKPSEYEKI AFQYGITDLRGMLKRLKRMRREEKK SAAFAKILDPAYQVDKGGRVRFVVE LADPKLEVKWYKNGQEIRPSTKYIF EHKGCQRILFINNCQMTDDSEYYVT AGDEKCSTELFVREPPIMVTKQLED TTAYCGERVELECEVSEDDANVKWF KNGEEIIPGPKSRYRIRVEGKKHIL IIEGATKADAAEYSVMTTGGQSSAK LSVDLKPLKILTPLTDQTVNLGKEI CLKCEISENIPGKWTKNGLPVQESD RLKVVHKGRIHKLVIANALTEDEGD YVFAPDAYNVTLPAKVHVIDPPKII LDGLDADNTVTVIAGNKLRLEIPIS GEPPPKAMWSRGDKAIMEGSGRIRT ESYPDSSTLVIDIAERDDSGVYHIN LKNEAGEAHASIKVKVVDFPDPPVA PTVTEVGDDWCIMNWEPPAYDGGSP ILGYFIERKKKQSSRWMRLNFDLCK ETTFEPKKMIEGVAYEVRIFAVNAI GISKPSMPSRPFVPLAVTSPPTLLT VDSVTDTTVTMRWRPPDHIGAAGLD GYVLEYCFEGTEDWIVANKDLIDKT KFTITGLPTDAKIFVRVKAVNAAGA SEPKYYSQPILVKEIIEPPKIRIPR HLKQTYIRRVGEAVNLVIPFQGKPR PELTWKKDGAEIDKNQINIRNSETD TIIFIRKAERSHSGKYDLQVKVDKF VETASIDIQIIDRPGPPQIVKIEDV WGENVALTWTPPKDDGNAAITGYTI QKADKKSMEWFTVIEHYHRTSATIT ELVIGNEYYFRVFSENMCGLSEDAT MTKESAVIARDGKIYKNPVYEDFDF SEAPMFTQPLVNTYAIAGYNATLNC SVRGNPKPKITWMKNKVAIVDDPRY RMFSNQGVCTLEIRKPSPYDGGTYC CKAVNDLGTVEIECKLEVKVIAQTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
