Recombinant Human NAGA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NAGA-5419H
• Product Overview: NAGA MS Standard C13 and N15-labeled recombinant protein (NP_000253) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.6 kDa
• AA Sequence: MLLKTVLLLGHVAQVLMLDNGLLQT PPMGWLAWERFRCNINCDEDPKNCI SEQLFMEMADRMAQDGWRDMGYTYL NIDDCWIGGRDASGRLMPDPKRFPH GIPFLADYVHSLGLKLGIYADMGNF TCMGYPGTTLDKVVQDAQTFAEWKV DMLKLDGCFSTPEERAQGYPKMAAA LNATGRPIAFSCSWPAYEGGLPPRV NYSLLADICNLWRNYDDIQDSWWSV LSILNWFVEHQDILQPVAGPGHWND PDMLLIGNFGLSLEQSRAQMALWTV LAAPLLMSTDLRTISAQNMDILQNP LMIKINQDPLGIQGRRIHKEKSLIE VYMRPLSNKASALVFFSCRTDMPYR YHSSLGQLNFTGSVIYEAQDVYSGD IISGLRDETNFTVIINPSGVVMWYL YPIKNLEMSQQTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NAGA alpha-N-acetylgalactosaminidase [ Homo sapiens (human) ]
• Official Symbol: NAGA
• Synonyms: NAGA; N-acetylgalactosaminidase, alpha-; alpha-N-acetylgalactosaminidase; D22S674; alpha-galactosidase B; Acetylgalactosaminidase, alpha-N- (alpha-galactosidase B); GALB
• Gene ID: 4668
• mRNA Refseq: NM_000262
• Protein Refseq: NP_000253
• MIM: 104170
• UniProt ID: P17050