| Description : |
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
58 kDa |
| AA Sequence : |
MATALMAVVLRAAAVAPRLRGRGGT GGARRLSCGARRRAARGTSPGRRLS TAWSQPQPPPEEYAGADDVSQSPVA EEPSWVPSPRPPVPHESPEPPSGRS LVQRDIQAFLNQCGASPGEARHWLT QFQTCHHSADKPFAVIEVDEEVLKC QQGVSSLAFALAFLQRMDMKPLVVL GLPAPTAPSGCLSFWEAKAQLAKSC KVLVDALRHNAAAAVPFFGGGSVLR AAEPAPHASYGGIVSVETDLLQWCL ESGSIPILCPIGETAARRSVLLDSL EVTASLAKALRPTKIIFLNNTGGLR DSSHKVLSNVNLPADLDLVCNAEWV STKERQQMRLIVDVLSRLPHHSSAV ITAASTLLTELFSNKGSGTLFKNAE RMLRVRSLDKLDQGRLVDLVNASFG KKLRDDYLASLRPRLHSIYVSEGYN AAAILTMEPVLGGTPYLDKFVVSSS RQGQGSGQMLWECLRRDLQTLFWRS RVTNPINPWYFKHSDGSFSNKQWIF FWFGLADIRDSYELVNHAKGLPDSF HKPASDPGSTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
