Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human NCALD Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : NCALD-2494H
Product Overview : NCALD MS Standard C13 and N15-labeled recombinant protein (NP_001035714) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 22.3 kDa
AA Sequence : MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSMEEFI RGAKSDPSIV RLLQCDPSSA GQFTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : NCALD neurocalcin delta [ Homo sapiens (human) ]
Official Symbol : NCALD
Synonyms : NCALD; neurocalcin delta; neurocalcin-delta; MGC33870; MGC74858;
Gene ID : 83988
mRNA Refseq : NM_001040624
Protein Refseq : NP_001035714
MIM : 606722
UniProt ID : P61601

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