Recombinant Human NCSTN Protein, MYC/DDK-tagged

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Recombinant Human NCSTN Protein, MYC/DDK-tagged

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Cat.No. : NCSTN-469H
Product Overview : Recombinant human NCSTN protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. [UniProtKB/Swiss-Prot Function]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 75.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : nicastrin [ Homo sapiens ]
Official Symbol : NCSTN
Synonyms : ATAG1874
Gene ID : 23385
mRNA Refseq : NM_015331.2
Protein Refseq : NP_056146.1
MIM : 605254
UniProt ID : Q92542

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