"NCSTN" Related Products


Recombinant Human NCSTN Protein, MYC/DDK-tagged

Cat.No.: NCSTN-469H
Product Overview: Recombinant human NCSTN protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. [UniProtKB/Swiss-Prot Function]
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass: 75.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: nicastrin [ Homo sapiens ]
Official Symbol: NCSTN
Synonyms: ATAG1874
Gene ID: 23385
mRNA Refseq: NM_015331.2
Protein Refseq: NP_056146.1
MIM: 605254
UniProt ID: Q92542

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