Recombinant Human NECTIN1 Protein, MYC/DDK-tagged

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Recombinant Human NECTIN1 Protein, MYC/DDK-tagged

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Cat.No. : NECTIN1-591H
Product Overview : Recombinant human NECTIN1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 54 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : nectin cell adhesion molecule 1[ Homo sapiens ]
Official Symbol : NECTIN1
Synonyms : CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12
Gene ID : 5818
mRNA Refseq : NM_002855.4
Protein Refseq : NP_002846.3
MIM : 600644
UniProt ID : Q15223

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