| Description : |
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
57.74 kDa |
| AA Sequence : |
MARAAALLPSRSPPTPLLWPLLLLL LLETGAQDVRVQVLPEVRGQLGGTV ELPCHLLPPVPGLYISLVTWQRPDA PANHQNVAAFHPKMGPSFPSPKPGS ERLSFVSAKQSTGQDTEAELQDATL ALHGLTVEDEGNYTCEFATFPKGSV RGMTWLRVIAKPKNQAEAQKVTFSQ DPTTVALCISKEGRPPARISWLSSL DWEAKETQVSGTLAGTVTVTSRFTL VPSGRADGVTVTCKVEHESFEEPAL IPVTLSVRYPPEVSISGYDDNWYLG RTDATLSCDVRSNPEPTGYDWSTTS GTFPTSAVAQGSQLVIHAVDSLFNT TFVCTVTNAVGMGRAEQVIFVRETP NTAGAGATGGIIGGIIAAIIATAVA ATGILICRQQRKEQTLQGAEEDEDL EGPPSYKPPTPKAKLEAQEMPSQLF TLGASEHSPLKTPYFDAGASCTEQE MPRYHELPTLEERSGPLHPGATSLG SPIPVPPGPPAVEDVSLDLEDEEGE EEEEYLDKINPIYDALSYSSPSDSY QGKGFVMSRAMYVTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
