Recombinant Human NEFH Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human NEFH Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : NEFH-2216H
Product Overview : NEFH MS Standard C13 and N15-labeled recombinant protein (NP_066554) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 111.7 kDa
AA Sequence : MMSFGGADAL LGAPFAPLHG GGSLHYALAR KGGAGGTRSA AGSSSGFHSW TRTSVSSVSA SPSRFRGAGA ASSTDSLDTL SNGPEGCMVA VATSRSEKEQ LQALNDRFAG YIDKVRQLEA HNRSLEGEAA ALRQQQAGRS AMGELYEREV REMRGAVLRL GAARGQLRLE QEHLLEDIAH VRQRLDDEAR QREEAEAAAR ALARFAQEAE AARVDLQKKA QALQEECGYL RRXHQEEVGE LLGQIQGSGA AQAQMQAETR DALKCDVTSA LREIRAQLEG HAVQSTLQSE EWFRVRLDRL SEAAKVNTDA MRSAQEEITE YRRQLQARTT ELEALKSTKD SLERQRSELE DRHQADIASY QEAIQQLDAE LRNTKWEMAA QLREYQDLLN VKMALDIEIA AYRKLLEGEE CRIGFGPIPF SLPEGLPKIP SVSTHIKVKS EEKIKVVEKS EKETVIVEEQ TEETQVTEEV TEEEEKEAKE EEGKEEEGGE EEEAEGGEEE TKSPPAEEAA SPEKEAKSPV KEEAKSPAEA KSPEKEEAKS PAEVKSPEKA KSPAKEEAKS PPEAKSPEKE EAKSPAEVKS PEKAKSPAKE EAKSPAEAKS PEKAKSPVKE EAKSLAEAKS PVKEEAKSPA EVKSPEKAKS PTKEEAKSPE KAKSPEKEEA KSPEKAKSPV KAEAKSPEKA KSPVKAEAKS PEKAKSPVKE EAKSPEKAKS PVKEEAKSPE KAKSPVKEEA KTPEKAKSPV KEEAKSPEKA KSPEKAKTLD VKSPEAKTPA KEEARSPADK FPEKAKSPVK EEVKSPEKAK SPLKEDAKAP EKEIPKKEEV KSPVKEEEKP QEVKVKEPPK KAEEEKAPAT PKTEEKKDSK KEEAPKKEAP KPKVEEKKEP AVEKPKESKV EAKKEEAEDK KKVPTPEKEA PAKVEVKEDA KPKEKTEVAK KEPDDAKAKE PSKPAEKKEA APEKKDTKEE KAKKPEEKPK TEAKAKEDDK TLSKEPSKPK AEKAEKSSST DQKDSKPPEK ATEDKAAKGK TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : NEFH neurofilament heavy [ Homo sapiens (human) ]
Official Symbol : NEFH
Synonyms : NEFH; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament heavy polypeptide; NF-H; 200 kDa neurofilament protein; neurofilament triplet H protein; NFH;
Gene ID : 4744
mRNA Refseq : NM_021076
Protein Refseq : NP_066554
MIM : 162230
UniProt ID : P12036

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