Recombinant Human NEFL Protein (Ser2-Asp543), N-His-SUMO tagged, Animal-free, Carrier-free
Cat.No. : | NEFL-233H |
Product Overview : | Recombinant Human NEFL Protein (Ser2-Asp543) with N-His-SUMO tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Neurofilaments (NF) are assembled as heteropolymers, found exclusively in neurons, and serve as axonal scaffolding. They are composed of three subunits, including NF-L (68 kDa), NF-M (95 kDa), and NF-H (115 kDa), that are essential for axonal growth and maintenance. Elevated NF-L levels in serum and CSF (cerebrospinal fluid) have been correlated with axonal damage in Multiple Sclerosis patients, serving as a prognostic marker. In addition, plasma NF-L concentrations were highly significantly higher in patients with Alzheimer’s disease. |
Source : | E. coli |
Species : | Human |
Tag : | N-His-SUMO |
Form : | Lyophilized |
Molecular Mass : | The protein has a calculated MW of 73.91 kDa. The protein migrates as 75 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ser2-Asp543 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >95% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | NEFL neurofilament, light polypeptide [ Homo sapiens (human) ] |
Official Symbol : | NEFL |
Synonyms : | NEFL; neurofilament, light polypeptide; neurofilament, light polypeptide 68kDa; neurofilament light polypeptide; CMT1F; CMT2E; NF68; NFL; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament protein, light chain; light molecular weight neurofilament protein; NF-L; FLJ53642; |
Gene ID : | 4747 |
mRNA Refseq : | NM_006158 |
Protein Refseq : | NP_006149 |
MIM : | 162280 |
UniProt ID : | P07196 |
Products Types
◆ Recombinant Protein | ||
NEFL-2574H | Recombinant Human NEFL protein(11-350 aa), N-MBP & C-His-tagged | +Inquiry |
NEFL-2484H | Recombinant Human NEFL Protein, His-tagged | +Inquiry |
NEFL-10563M | Recombinant Mouse Nefl Protein, Myc/DDK-tagged | +Inquiry |
NEFL-2815R | Recombinant Rhesus Macaque NEFL Protein, His (Fc)-Avi-tagged | +Inquiry |
NEFL-2573H | Recombinant Human NEFL protein(91-510 aa), C-His-tagged | +Inquiry |
◆ Native Protein | ||
NFL-01P | Native Pig NFL Protein (549 AA) | +Inquiry |
NEFL-181B | Native bovine NEFL | +Inquiry |
◆ Lysates | ||
NEFL-3884HCL | Recombinant Human NEFL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket