Recombinant Human NEK6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NEK6-4335H
• Product Overview: NEK6 MS Standard C13 and N15-labeled recombinant protein (NP_055212) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.7 kDa
• AA Sequence: MAGQPGHMPHGGSSNNLCHTLGPVH PPDPQRHPNTLSFRCSLADFQIEKK IGRGQFSEVYKATCLLDRKTVALKK VQIFEMMDAKARQDCVKEIGLLKQL NHPNIIKYLDSFIEDNELNIVLELA DAGDLSQMIKYFKKQKRLIPERTVW KYFVQLCSAVEHMHSRRVMHRDIKP ANVFITATGVVKLGDLGLGRFFSSE TTAAHSLVGTPYYMSPERIHENGYN FKSDIWSLGCLLYEMAALQSPFYGD KMNLFSLCQKIEQCDYPPLPGEHYS EKLRELVSMCICPDPHQRPDIGYVH QVAKQMHIWMSSTTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NEK6 NIMA related kinase 6 [ Homo sapiens (human) ]
• Official Symbol: NEK6
• Synonyms: NEK6; NIMA (never in mitosis gene a)-related kinase 6; SID6-1512
• Gene ID: 10783
• mRNA Refseq: NM_014397
• Protein Refseq: NP_055212
• MIM: 604884
• UniProt ID: Q9HC98