Recombinant Human NELFB Protein, MYC/DDK-tagged

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Recombinant Human NELFB Protein, MYC/DDK-tagged

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Cat.No. : NELFB-561H
Product Overview : Recombinant human NELFB protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 65.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : negative elongation factor complex member B[ Homo sapiens ]
Official Symbol : NELFB
Synonyms : COBRA1; NELF-B
Gene ID : 25920
mRNA Refseq : NM_015456.3
Protein Refseq : NP_056271.2
MIM : 611180
UniProt ID : Q8WX92

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