"NF2" Related Products


Recombinant Human NF2 protein, GST-tagged

Cat.No.: NF2-22H
Product Overview: Recombinant Human NF2(1 a.a. - 82 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
Description: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Source: Wheat Germ
Species: Human
Tag : GST
Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass: 34.76 kDa
Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: NF2 neurofibromin 2 (merlin) [ Homo sapiens ]
Official Symbol: NF2
Synonyms: NF2; neurofibromin 2 (merlin); neurofibromin 2 (bilateral acoustic neuroma); merlin; moesin ezrin radixin like; schwannomin; schwannomerlin; neurofibromin-2; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; ACN; SCH; BANF;
Gene ID: 4771
mRNA Refseq: NM_000268
Protein Refseq: NP_000259
MIM: 607379
UniProt ID: P35240
Chromosome Location: 22q12.2
Pathway: ErbB2/ErbB3 signaling events, organism-specific biosystem;
Function: cytoskeletal protein binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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