Recombinant Human NFATC2 Protein, His tagged

• Cat.No.: NFATC2-23H
• Product Overview: Recombinant human NFATC2, fused to His-tag at C-terminus (396-678 aa), was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 396-678 aa
• Description: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
• Form: Liquid in Phosphate-Buffered Saline (pH 7.4) containing 40% glycerol, 1mM DTT
• Molecular Mass: 33.1 kDa (290aa)
• AASequence: PLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by absorbance at 280nm)

Gene Information

• Gene Name: NFATC2 nuclear factor of activated T cells 2 [ Homo sapiens (human) ]
• Official Symbol: NFATC2
• Synonyms: NFATC2; nuclear factor of activated T cells 2; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; T cell transcription factor NFAT1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; preexisting nuclear factor of activated T-cells 2; JCOSL; NFAT1; NFATP
• Gene ID: 4773
• mRNA Refseq: NM_173091
• Protein Refseq: NP_775114
• MIM: 600490
• UniProt ID: Q13469