Recombinant Human NFATC2 protein, MYC/DDK-tagged
Cat.No. : | NFATC2-181H |
Product Overview : | Recombinant Human NFATC2, transcript variant D, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
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Description : | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 97.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 [ Homo sapiens ] |
Official Symbol : | NFATC2 |
Synonyms : | NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, cytoplasmic 2; NF ATP; NFAT1; NFATp; NF-ATc2; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component; NFATP; |
Gene ID : | 4773 |
mRNA Refseq : | NM_001136021 |
Protein Refseq : | NP_001129493 |
MIM : | 600490 |
UniProt ID : | Q13469 |
Chromosome Location : | 20q13.2 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; |
Function : | DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; |
Products Types
◆ Recombinant Protein | ||
Nfatc2-4388M | Recombinant Mouse Nfatc2 Protein, Myc/DDK-tagged | +Inquiry |
NFATC2-391H | Recombinant Human NFATC2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
NFATC2-18H | Recombinant Human NFATC2 protein, MYC/DDK-tagged | +Inquiry |
NFATC2-182H | Recombinant Human NFATC2 protein, MYC/DDK-tagged | +Inquiry |
NFATC2-29251TH | Recombinant Human NFATC2, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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