Recombinant Human NFE4 Protein, MYC/DDK-tagged NFE4-747H

Specification Gene Information Related Products

Cat.No. :	NFE4-747H
Product Overview :	Recombinant human NFE4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description :	The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008].
Source :	HEK293
Species :	Human
Tag :	MYC/DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass :	18.9 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name :	nuclear factor, erythroid 4[ Homo sapiens ]
Official Symbol :	NFE4
Synonyms :	NF-E4; NF-E4
Gene ID :	58160
Protein Refseq :	NP_001078855

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