- Human(2)
Recombinant Human NFE4 Protein, MYC/DDK-tagged
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Cat.No. : | NFE4-747H |
Product Overview : | Recombinant human NFE4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
Description : | The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 18.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | nuclear factor, erythroid 4[ Homo sapiens ] |
Official Symbol : | NFE4 |
Synonyms : | NF-E4; NF-E4 |
Gene ID : | 58160 |
Protein Refseq : | NP_001078855 |
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