Recombinant Human NKX2-2, GST-tagged

• Cat.No.: NKX2-2-1303H
• Product Overview: Recombinant Human NKX2-2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-129aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: NKX2-2 NK2 homeobox 2 [ Homo sapiens ]
• Official Symbol: NKX2-2
• Synonyms: NKX2-2; NK2 homeobox 2; NK 2 (Drosophila) homolog B , NK2 transcription factor related, locus 2 (Drosophila) , NKX2B; homeobox protein Nkx-2.2; NKX2.2; NK-2 homolog B; homeobox protein NK-2 homolog B; NK2 transcription factor-like protein B; NK2 transcription factor related, locus 2; NKX2B
• Gene ID: 4821
• mRNA Refseq: NM_002509
• Protein Refseq: NP_002500
• MIM: 604612
• UniProt ID: O95096
• Chromosome Location: 20p11.22
• Pathway: Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in beta cells, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem
• Function: chromatin binding; core promoter proximal region DNA binding; sequence-specific DNA binding; transcription coactivator activity; transcription factor binding