Recombinant Mouse NKX2-2 Protein (1-273 aa), His-SUMO-tagged

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Recombinant Mouse NKX2-2 Protein (1-273 aa), His-SUMO-tagged

NKX2-2 Related Products

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Cat.No. : NKX2-2-1766M
Product Overview : Recombinant Mouse NKX2-2 Protein (1-273 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length.
Description : Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter.
Source : E. coli
Species : Mouse
Tag : His-SUMO
Form : Tris-based buffer,50% glycerol
Molecular Mass : 46.1 kDa
Protein length : 1-273 aa
AA Sequence : MSLTNTKTGF SVKDILDLPD TNDEDGSVAE GPEEESEGPE PAKRAGPLGQ GALDAVQSLP LKSPFYDSSD NPYTRWLAST EGLQYSLHGL AASAPPQDSS SKSPEPSADE SPDNDKETQG GGGDAGKKRK RRVLFSKAQT YELERRFRQQ RYLSAPEREH LASLIRLTPT QVKIWFQNHR YKMKRARAEK GMEVTPLPSP RRVAVPVLVR DGKPCHALKA QDLAAATFQA GIPFSAYSAQ SLQHMQYNAQ YSSASTPQYP TAHPLVQAQQ WTW
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) [ Mus musculus ]
Official Symbol : NKX2-2
Synonyms : NKX2-2; homeobox protein Nkx2-2; Nkx2.2; tinman; Nkx-2.2;
Gene ID : 18088
mRNA Refseq : NM_001077632
Protein Refseq : NP_001071100
UniProt ID : P42586

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