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Recombinant Mouse NKX2-2 Protein (1-273 aa), His-SUMO-tagged

Cat.No. : NKX2-2-1766M
Product Overview : Recombinant Mouse NKX2-2 Protein (1-273 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length.
  • Specification
  • Gene Information
  • Related Products
Description : Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter.
Source : E. coli
Species : Mouse
Tag : His-SUMO
Form : Tris-based buffer,50% glycerol
Molecular Mass : 46.1 kDa
Protein length : 1-273 aa
AA Sequence : MSLTNTKTGFSVKDILDLPDTNDED GSVAEGPEEESEGPEPAKRAGPLGQ GALDAVQSLPLKSPFYDSSDNPYTR WLASTEGLQYSLHGLAASAPPQDSS SKSPEPSADESPDNDKETQGGGGDA GKKRKRRVLFSKAQTYELERRFRQQ RYLSAPEREHLASLIRLTPTQVKIW FQNHRYKMKRARAEKGMEVTPLPSP RRVAVPVLVRDGKPCHALKAQDLAA ATFQAGIPFSAYSAQSLQHMQYNAQ YSSASTPQYPTAHPLVQAQQWTW
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) [ Mus musculus ]
Official Symbol : NKX2-2
Synonyms : NKX2-2; homeobox protein Nkx2-2; Nkx2.2; tinman; Nkx-2.2;
Gene ID : 18088
mRNA Refseq : NM_001077632
Protein Refseq : NP_001071100
UniProt ID : P42586

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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