Recombinant Human NKX6-1 Protein, GST-tagged

• Cat.No.: NKX6-1-5905H
• Product Overview: Human NKX6-1 full-length ORF ( AAI60030.1, 1 a.a. - 367 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.77 kDa
• AA Sequence: MLAVGAMEGTRQSAFLLSSPPLAAL HSMAEMKTPLYPAAYPPLPAGPPSS SSSSSSSSSPSPPLGTHNPGGLKPP ATGGLSSLGSPPQQLSAATPHGIND ILSRPSMPVASGAALPSASPSGSSS SSSSSASASSASAAAAAAAAAAAAA SSPAGLLAGLPRFSSLSPPPPPPGL YFSPSAAAVAAVGRYPKPLAELPGR TPIFWPGVMQSPPWRDARLACTPHQ GSILLDKDGKRKHTRPTFSGQQIFA LEKTFEQTKYLAGPERARLAYSLGM TESQVKVWFQNRRTKWRKKHAAEMA TAKKKQDSETERLKGASENEEEDDD YNKPLDPNSDDEKITQLLKKHKSSS GGGGGLLLHASEPESSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NKX6-1 NK6 homeobox 1 [ Homo sapiens ]
• Official Symbol: NKX6-1
• Synonyms: NKX6-1; NK6 homeobox 1; NK homeobox (Drosophila), family 6, A , NK6 transcription factor related, locus 1 (Drosophila) , NKX6A; homeobox protein Nkx-6.1; Nkx6.1; NK homeobox, family 6, A; homeobox protein NK-6 homolog A; NK homeo box, family 6, member A; NK6 transcription factor homolog A; NK6 transcription factor related, locus 1; NKX6A; NKX6.1
• Gene ID: 4825
• mRNA Refseq: NM_006168
• Protein Refseq: NP_006159
• MIM: 602563
• UniProt ID: P78426