"NLRC5" Related Products

Recombinant Human NLRC5 protein, His-tagged

Cat.No.: NLRC5-489H
Product Overview: Recombinant Human NLRC5 fused with His tag was expressed in HEK293.
Description: This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
Source: HEK293
Species: Human
Tag: His
Form: Tris-based buffer,50% glycerol
Purity: >90% ( SDS-PAGE )
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.
Gene Name: NLRC5 NLR family, CARD domain containing 5 [ Homo sapiens ]
Official Symbol: NLRC5
Synonyms: NLRC5; NLR family, CARD domain containing 5; protein NLRC5; CLR16.1; FLJ21709; NOD like receptor C5; NOD27; nucleotide binding oligomerization domain; leucine rich repeat and CARD domain containing 5; NOD-like receptor C5; caterpiller protein 16.1; nucleotide-binding oligomerization domains 27; nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; NOD4; FLJ39711;
Gene ID: 84166
mRNA Refseq: NM_032206
Protein Refseq: NP_115582
MIM: 613537
UniProt ID: Q86WI3
Chromosome Location: 16q13
Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem;
Function: ATP binding; RNA polymerase II core promoter sequence-specific DNA binding; nucleotide binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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