Active Recombinant Human NNMT Protein, His-tagged, Bioactivity Validated
Cat.No. : | NNMT-234H |
Product Overview : | Recombinant Human NNMT(1-264aa) fused with His tag at N-terminal was expressed in E. coli. Bioactivity Validated. |
- Specification
- Gene Information
- Related Products
Description : | NNMT(Nicotinamide N-methyltransferase) belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. It is predominantly expressed in the liver, and a lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. NNMT catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol |
Bio-activity : | Specific activity is > 100 nmol/min/mg, and is defined as the amount of enzyme that transfer 1.0 nmole of methyl group per minute at 37C. |
Molecular Mass : | 37.7 kDa (284aa), confirmed by MALDI-TOF |
Protein length : | 1-264aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC LDGVKGDLLI DIGSGPTIYQ LLSACESFKE IVVTDYSDQN LQELEKWLKK EPEAFDWSPV VTYVCDLEGN RVKGPEKEEK LRQAVKQVLK CDVTQSQPLG AVPLPPADCV LSTLCLDAAC PDLPTYCRAL RNLGSLLKPG GFLVIMDALK SSYYMIGEQK FSSLPLGREA VEAAVKEAGY TIEWFEVISQ SYSSTMANNE GLFSLVARKL SRPL |
Purity : | > 95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Absorbance at 280nm) |
Gene Name : | NNMT nicotinamide N-methyltransferase [ Homo sapiens ] |
Official Symbol : | NNMT |
Synonyms : | NNMT; nicotinamide N-methyltransferase; |
Gene ID : | 4837 |
mRNA Refseq : | NM_006169 |
Protein Refseq : | NP_006160 |
MIM : | 600008 |
UniProt ID : | P40261 |
Products Types
◆ Recombinant Protein | ||
NNMT-185H | Recombinant Human NNMT Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Nnmt-781M | Recombinant Mouse Nnmt Protein, His-tagged | +Inquiry |
NNMT-034H | Recombinant Human NNMT Protein, His/SUMO-tagged | +Inquiry |
Nnmt-4449M | Recombinant Mouse Nnmt Protein, Myc/DDK-tagged | +Inquiry |
NNMT-5956H | Recombinant Human NNMT Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
NNMT-3779HCL | Recombinant Human NNMT 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2215 | N'-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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