Recombinant Human NOS3 cell lysate

• Cat.No.: NOS3-1206HCL

Specification

• Description: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NOS3 nitric oxide synthase 3 (endothelial cell) [ Homo sapiens ]
• Official Symbol: NOS3
• Synonyms: NOS3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase, endothelial; ECNOS; endothelial nitric oxide synthase; eNOS; cNOS; EC-NOS; NOSIII; NOS type III; endothelial NOS; constitutive NOS
• Gene ID: 4846
• mRNA Refseq: NM_000603
• Protein Refseq: NP_000594
• UniProt ID: P29474
• Chromosome Location: 7q36
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Hemostasis, organism-specific biosystem
• Function: FMN binding; NADP binding; actin monomer binding; arginine binding; cadmium ion binding; calmodulin binding; flavin adenine dinucleotide binding; heme binding; metal ion binding; nitric-oxide synthase activity; oxidoreductase activity; protein binding; tetrahydrobiopterin binding