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Recombinant Human NOVA1 protein, His-tagged

Cat.No. : NOVA1-7989H
Product Overview : Recombinant Human NOVA1 aa. (Ala295~Gly510) fused with N-terminal His tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 25kDa as determined by SDS-PAGE reducing conditions.
Protein length : Ala295~Gly510
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >94%
Characteristic : The isoelectric point is 8.9.
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200μg/mL
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : NOVA1 NOVA alternative splicing regulator 1 [ Homo sapiens (human) ]
Official Symbol : NOVA1
Synonyms : Nova-1; neuro-oncological ventral antigen 1; onconeural ventral antigen 1; paraneoplastic Ri antigen; ventral neuron-specific protein 1; RNA-binding protein Nova-1
Gene ID : 4857
mRNA Refseq : NM_002515.2
Protein Refseq : NP_002506.2
UniProt ID : P51513

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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