Recombinant Human NOVA1

• Cat.No.: NOVA1-29728TH
• Product Overview: Recombinant full length Human Nova1 with N terminal proprietary tag, predicted mwt: 81.51 kDa.

Specification

• Description: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
• Protein length: 508 amino acids
• Molecular Weight: 81.510kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Brain.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTK RTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKS SPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ SGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALN TLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFG AASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKG GKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA TQAAQYLITQRITYEQGVRAANPQKVG
• Sequence Similarities: Contains 3 KH domains.

Gene Information

• Gene Name: NOVA1 neuro-oncological ventral antigen 1 [ Homo sapiens ]
• Official Symbol: NOVA1
• Synonyms: NOVA1; neuro-oncological ventral antigen 1; RNA-binding protein Nova-1
• Gene ID: 4857
• mRNA Refseq: NM_002515
• Protein Refseq: NP_002506
• MIM: 602157
• Uniprot ID: P51513
• Chromosome Location: 14q12
• Function: RNA binding