Recombinant Human NOVA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NOVA1-4417H
• Product Overview: NOVA1 MS Standard C13 and N15-labeled recombinant protein (NP_006480) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49.1 kDa
• AA Sequence: MMAAAPIQQNGTHTGVPIDLDPPDS RKRPLEAPPEAGSTKRTNTGEDGQY FLKVLIPSYAAGSIIGKGGQTIVQL QKETGATIKLSKSKDFYPGTTERVC LIQGTVEALNAVHGFIAEKIREMPQ NVAKTEPVSILQPQTTVNPDRIKQV KIIVPNSTAGLIIGKGGATVKAVME QSGAWVQLSQKPDGINLQERVVTVS GEPEQNRKAVELIIQKIQEDPQSGS CLNISYANVTGPVANSNPTGSPYAN TAEVLPTAAAAAGLLGHANLAGVAA FPAVLSGFTGNDLVAITSALNTLAS YGYNLNTLGLGLSQAAATGALAAAA ASANPAAAAANLLATYASEASASGS TAGGTAGTFALGSLAAATAATNGYF GAASPLAASAILGTEKSTDGSKDVV EIAVPENLVGAILGKGGKTLVEYQE LTGARIQISKKGEFVPGTRNRKVTI TGTPAATQAAQYLITQRITYEQGVR AANPQKVGTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NOVA1 neuro-oncological ventral antigen 1 [ Homo sapiens (human) ]
• Official Symbol: NOVA1
• Synonyms: NOVA1; neuro-oncological ventral antigen 1; RNA-binding protein Nova-1; paraneoplastic Ri antigen; onconeural ventral antigen 1; ventral neuron-specific protein 1; Nova-1
• Gene ID: 4857
• mRNA Refseq: NM_006489
• Protein Refseq: NP_006480
• MIM: 602157
• UniProt ID: P51513