Recombinant Human NPC2 protein, His & GST-tagged

• Cat.No.: NPC2-1811H
• Product Overview: Recombinant Human NPC2 aa. (Glu20~Leu151 (Accession # P61916)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
• Source: E. coli
• Species: Human
• Tag: His & GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.6kDa
• Protein length: Glu20~Leu151 (Accession # P61916)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 7

Gene Information

• Gene Name: NPC2 NPC intracellular cholesterol transporter 2 [ Homo sapiens (human) ]
• Official Symbol: NPC2
• Synonyms: NPC2; NPC intracellular cholesterol transporter 2; HE1; EDDM1; epididymal secretory protein E1; Niemann-Pick disease type C2 protein; epididymal protein 1; human epididymis-specific protein 1; tissue-specific secretory protein
• Gene ID: 10577
• mRNA Refseq: NM_006432.3
• Protein Refseq: NP_006423.1
• UniProt ID: P61916