Recombinant Human NRDC Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NRDC-5190H
• Product Overview: NRD1 MS Standard C13 and N15-labeled recombinant protein (NP_002516) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 139.2 kDa
• AA Sequence: MLRRVTVAAVCATRRKLCEAGRDVA ALWGIETRGRCEDSAAARPFPILAM PGRNKAKSTCSCPDLQPNGQDLGEN SRVARLGADESEEEGRRGSLSNAGD PEIVKSPSDPKQYRYIKLQNGLQAL LISDLSNMEGKTGNTTDDEEEEEVE EEEEDDDEDSGAEIEDDDEEGFDDE DEFDDEHDDDLDTEDNELEELEERA EARKKTTEKQQLQSLFLLWSKLTDR LWFKSTYSKMSSTLLVETRNLYGVV GAESRSAPVQHLAGWQAEEQQGETD TVLSAAALCVGVGSFADPDDLPGLA HFLEHMVFMGSLKYPDENGFDAFLK KHGGSDNASTDCERTVFQFDVQRKY FKEALDRWAQFFIHPLMIRDAIDRE VEAVDSEYQLARPSDANRKEMLFGS LARPGHPMGKFFWGNAETLKHEPRK NNIDTHARLREFWMRYYSSHYMTLV VQSKETLDTLEKWVTEIFSQIPNNG LPRPNFGHLTDPFDTPAFNKLYRVV PIRKIHALTITWALPPQQQHYRVKP LHYISWLVGHEGKGSILSFLRKKCW ALALFGGNGETGFEQNSTYSVFSIS ITLTDEGYEHFYEVAYTVFLYLKML QKLGPEKRIFEEIRKIEDNEFHYQE QTDPVEYVENMCENMQLYPLQDILT GDQLLFEYKPEVIGEALNQLVPQKA NLVLLSGANEGKCDLKEKWFGTQYS IEDIENSWAELWNSNFELNPDLHLP AENKYIATDFTLKAFDCPETEYPVK IVNTPQGCLWYKKDNKFKIPKAYIR FHLISPLIQKSAANVVLFDIFVNIL THNLAEPAYEADVAQLEYKLAAGEH GLIIRVKGFNHKLPLLFQLIIDYLA EFNSTPAVFTMITEQLKKTYFNILI KPETLAKDVRLLILEYARWSMIDKY QALMDGLSLESLLSFVKEFKSQLFV EGLVQGNVTSTESMDFLKYVVDKLN FKPLEQEMPVQFQVVELPSGHHLCK VKALNKGDANSEVTVYYQSGTRSLR EYTLMELLVMHMEEPCFDFLRTKQT LGYHVYPTCRNTSGILGFSVTVGTQ ATKYNSEVVDKKIEEFLSSFEEKIE NLTEEAFNTQVTALIKLKECEDTHL GEEVDRNWNEVVTQQYLFDRLAHEI EALKSFSKSDLVNWFKAHRGPGSKM LSVHVVGYGKYELEEDGSPSSEDSN SSCEVMQLTYLPTSPLLADCIIPIT DIRAFTTTLNLLPYHKIVKTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NRDC nardilysin convertase [ Homo sapiens (human) ]
• Official Symbol: NRDC
• Synonyms: NRDC; nardilysin convertase; NRD1; hNRD1; hNRD2; nardilysin; NRD convertase; nardilysin (N-arginine dibasic convertase); EC 3.4.24.61
• Gene ID: 4898
• mRNA Refseq: NM_002525
• Protein Refseq: NP_002516
• MIM: 602651
• UniProt ID: O43847