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Recombinant Human NRG1 Protein, His-tagged

Cat.No. : NRG1-709H
Product Overview : Recombinant Human NRG1, transcript variant GGF2, fused with His tag at C-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.4
Molecular Mass : 8.2kD
AA Sequence : SGKKPESAAGSQSPALPPQLKEMKS QESAAGSKLVLRCETSSEYSSLRFK WFKNGNELNRKNKPQNIKIQKKPGK SELRINKASLADSGEYMCKVISKLG NDSASANITIVESNEIITGMPASTE GAYVSSESPIRISVSTEGANTSSST STSTTGTSHLVKCAEKEKTFCVNGG ECFMVKDLSNPSRYLCKCPNEFTGD RCQNYVMASFYSTSTPFLSLPEVDH HHHHH*
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Gene Name : NRG1 neuregulin 1 [ Homo sapiens ]
Official Symbol : NRG1
Synonyms : NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131;
Gene ID : 3084
mRNA Refseq : NM_001159995
Protein Refseq : NP_001153467
MIM : 142445
UniProt ID : Q02297

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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