Recombinant Human NRG2 Protein (112-405 aa), His-tagged

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Recombinant Human NRG2 Protein (112-405 aa), His-tagged

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Cat.No. : NRG2-1741H
Product Overview : Recombinant Human NRG2 Protein (112-405 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.
Description : Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 34.8 kDa
Protein length : 112-405 aa
AA Sequence : CYSPSLKSVQ DQAYKAPVVV EGKVQGLVPA GGSSSNSTRE PPASGRVALV KVLDKWPLRS GGLQREQVIS VGSCVPLERN QRYIFFLEPT EQPLVFKTAF APLDTNGKNL KKEVGKILCT DCATRPKLKK MKSQTGQVGE KQSLKCEAAA GNPQPSYRWF KDGKELNRSR DIRIKYGNGR KNSRLQFNKV KVEDAGEYVC EAENILGKDT VRGRLYVNSV STTLSSWSGH ARKCNETAKS YCVNGGVCYY IEGINQLSCK CPNGFFGQRC LEKLPLRLYM PDPKQKAEEL YQKR
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : NRG2 neuregulin 2 [ Homo sapiens ]
Official Symbol : NRG2
Synonyms : NRG2; neuregulin 2; Don 1; HRG2; NTAK; pro-NRG2; divergent of neuregulin-1; DON1;
Gene ID : 9542
mRNA Refseq : NM_001184935
Protein Refseq : NP_001171864
MIM : 603818
UniProt ID : O14511

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